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FAM127A

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Protein-coding gene in the species Homo sapiens
RTL8C
Identifiers
AliasesRTL8C, CXX1, MAR8C, MART8C, Mar8, Mart8, FAM127A, family with sequence similarity 127 member A, SIRH5, retrotransposon Gag like 8C
External IDsOMIM: 300213; MGI: 1920115; HomoloGene: 124163; GeneCards: RTL8C; OMA:RTL8C - orthologs
Gene location (Human)
X chromosome (human)
Chr.X chromosome (human)
X chromosome (human)Genomic location for RTL8CGenomic location for RTL8C
BandXq26.3Start135,032,355 bp
End135,033,546 bp
Gene location (Mouse)
X chromosome (mouse)
Chr.X chromosome (mouse)
X chromosome (mouse)Genomic location for RTL8CGenomic location for RTL8C
BandX|X A5Start52,609,999 bp
End52,610,399 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • Brodmann area 10

  • frontal pole

  • right frontal lobe

  • Hypothalamus

  • cingulate gyrus

  • anterior cingulate cortex

  • apex of heart

  • Amygdala

  • nucleus accumbens

  • left ventricle
Top expressed in
  • Hypothalamus

  • striatum of neuraxis

  • adrenal gland

  • Cortex of frontal lobe

  • cerebellar cortex

  • olfactory bulb

  • superior frontal gyrus

  • hippocampus proper

  • primary visual cortex

  • lens
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

8933

72865

Ensembl

ENSG00000134590

ENSMUSG00000051851

UniProt

O15255

Q9D6I0

RefSeq (mRNA)

NM_003928
NM_001078171

NM_028375

RefSeq (protein)

NP_001071639

NP_082651

Location (UCSC)Chr X: 135.03 – 135.03 MbChr X: 52.61 – 52.61 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

CAAX box protein 1 is a protein that in humans is encoded by the FAM127A gene.


References

  1. ^ GRCh38: Ensembl release 89: ENSG00000134590Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000051851Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Frattini A, Faranda S, Zucchi I, Vezzoni P (Jan 1998). "A low-copy repeat in Xq26 represents a novel putatively prenylated protein gene (CXX1) and its pseudogenes (DXS9914, DXS9915, and DXS9916)". Genomics. 46 (1): 167–9. doi:10.1006/geno.1997.5006. PMID 9403077.
  6. Brandt J, Schrauth S, Veith AM, Froschauer A, Haneke T, Schultheis C, Gessler M, Leimeister C, Volff JN (Apr 2005). "Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals". Gene. 345 (1): 101–11. doi:10.1016/j.gene.2004.11.022. PMID 15716091.
  7. Brandt J, Veith AM, Volff JN (Aug 2005). "A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes". Cytogenet Genome Res. 110 (1–4): 307–17. doi:10.1159/000084963. PMID 16093683. S2CID 38398479.
  8. "Entrez Gene: FAM127A family with sequence similarity 127, member A".

Further reading


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