Ferric-chelate reductase (NADPH)

Ferric-chelate reductase (NADPH) (EC 1.16.1.9, ferric chelate reductase, iron chelate reductase, NADPH:Fe-EDTA reductase, NADPH-dependent ferric reductase, yqjH (gene)) is an enzyme with systematic name Fe(II):NADP oxidoreductase. This enzyme catalyses the following chemical reaction

2 Fe(II) + 2 apo-siderophore + NADP + H

\rightleftharpoons

2 Fe(III)-siderophore + NADPH

Ferric-chelate reductase contains FAD.

References

Bamford VA, Armour M, Mitchell SA, Cartron M, Andrews SC, Watson KA (September 2008). "Preliminary X-ray diffraction analysis of YqjH from Escherichia coli: a putative cytoplasmic ferri-siderophore reductase". Acta Crystallographica Section F. 64 (Pt 9): 792–6. doi:10.1107/S174430910802352X. PMC 2531270. PMID 18765906.
Wang S, Wu Y, Outten FW (January 2011). "Fur and the novel regulator YqjI control transcription of the ferric reductase gene yqjH in Escherichia coli". Journal of Bacteriology. 193 (2): 563–74. doi:10.1128/JB.01062-10. PMC 3019823. PMID 21097627.
Miethke M, Hou J, Marahiel MA (December 2011). "The siderophore-interacting protein YqjH acts as a ferric reductase in different iron assimilation pathways of Escherichia coli". Biochemistry. 50 (50): 10951–64. doi:10.1021/bi201517h. PMID 22098718.

External links

Ferric-chelate+reductase+(NADPH) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

v t e Other oxidoreductases (EC 1.15–1.21)
1.15: Acting on superoxide as acceptor	Superoxide dismutase SOD1 SOD2 SOD3
1.16: Oxidizing metal ions	Ceruloplasmin (Methionine synthase) reductase
1.17: Acting on CH or CH2 groups	Xanthine oxidase Ribonucleotide reductase 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase 7-Hydroxymethyl chlorophyll a reductase
1.18: Acting on iron–sulfur proteins as donors	Nitrogenase
1.19: Acting on reduced flavodoxin as donor	Nitrogenase (flavodoxin)
1.20: Acting on phosphorus or arsenic in donors	Glutaredoxin GLRX GLRX2 GLRX3 GLRX5
1.21: Acting on X-H and Y-H to form an X-Y bond	Isopenicillin N synthase Columbamine oxidase Reticuline oxidase Sulochrin oxidase (+)-bisdechlorogeodin-forming (-)-bisdechlorogeodin-forming Aureusidin synthase Tetrahydrocannabinolic acid synthase Cannabidiolic acid synthase Dichlorochromopyrrolate synthase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

Portal:

Biology

Category:

EC 1.16.1

Misplaced Pages

Ferric-chelate reductase (NADPH)

See also

References

External links