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Fumarylacetoacetic acid

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Fumarylacetoacetic acid
Names
Preferred IUPAC name (2E)-4,6-Dioxooct-2-enedioic acid
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
MeSH Fumarylacetoacetate
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C8H8O6/c9-5(1-2-7(11)12)3-6(10)4-8(13)14/h1-2H,3-4H2,(H,11,12)(H,13,14)/b2-1+Key: GACSIVHAIFQKTC-OWOJBTEDSA-N
  • InChI=1/C8H8O6/c9-5(1-2-7(11)12)3-6(10)4-8(13)14/h1-2H,3-4H2,(H,11,12)(H,13,14)/b2-1+Key: GACSIVHAIFQKTC-OWOJBTEDBU
SMILES
  • O=C(\C=C\C(=O)O)CC(=O)CC(=O)O
Properties
Chemical formula C8H8O6
Molar mass 200.146 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkverify (what is  ?) Infobox references
Chemical compound

Fumarylacetoacetic acid (fumarylacetoacetate) is an intermediate in the metabolism of tyrosine. It is formed through the conversion of maleylacetoacetate into fumarylacetoacetate by the enzyme maleylacetoacetate isomerase.

See also

References

  1. W. E. Knox and M. LeMay-Knox (1951). "The oxidation in liver of l-tyrosine to acetoacetate through p-hydroxyphenylpyruvate and homogentisic acid". Biochem. J. 49 (5): 686–693. doi:10.1042/bj0490686. PMC 1197578. PMID 14886367.
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