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Furanomycin

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Furanomycin
Names
Systematic IUPAC name (S)-Aminoacetic acid
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChemSpider
PubChem CID
UNII
InChI
  • InChI=1S/C7H11NO3/c1-4-2-3-5(11-4)6(8)7(9)10/h2-6H,8H2,1H3,(H,9,10)/t4-,5+,6-/m0/s1Key: PNOKUGWGMLEAPE-JKUQZMGJSA-N
  • InChI=1/C7H11NO3/c1-4-2-3-5(11-4)6(8)7(9)10/h2-6H,8H2,1H3,(H,9,10)/t4-,5+,6-/m0/s1Key: PNOKUGWGMLEAPE-JKUQZMGJBF
SMILES
  • C1C=C(O1)(C(=O)O)N
Properties
Chemical formula C7H11NO3
Molar mass 157.169 g·mol
Density 1.238 g/mL
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒N verify (what is  ?) Infobox references
Chemical compound
This article is missing information about natural sources (Streptomyces L-803 & Pseudomonas fluorescens SBW25), purpose. Please expand the article to include this information. Further details may exist on the talk page. (November 2023)

Furanomycin is an isoleucine—tRNA ligase inhibitor.

References

  1. Katagiri, Ken; Tori, Kazuo; Kimura, Yasuo; Yoshida, Tadashi; Nagasaki, Tohru; Minato, Hitoshi (1967). "A New Antibiotic. Furanomycin, an Isoleucine Antagonist". Journal of Medicinal Chemistry. 10 (6): 1149–1154. doi:10.1021/jm00318a035. PMID 4861779.
  2. Tanaka K, Tamaki M, Watanabe S (November 1969). "Effect of furanomycin on the synthesis of isoleucyl-tRNA". Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis. 195 (1): 244–245. doi:10.1016/0005-2787(69)90621-2. PMID 4982424.
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