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GPRASP1
Identifiers
Aliases	GPRASP1, GASP, GASP-1, GASP1, G protein-coupled receptor associated sorting protein 1
External IDs	OMIM: 300417; MGI: 1917418; HomoloGene: 8809; GeneCards: GPRASP1; OMA:GPRASP1 - orthologs
Gene location (Human) Chr. X chromosome (human) Band Xq22.1 Start 102,651,092 bp End 102,659,083 bp
Gene location (Mouse) Chr. X chromosome (mouse) Band X|X F1 Start 134,643,482 bp End 134,704,223 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in middle temporal gyrus Brodmann area 23 endothelial cell cerebellar vermis superior frontal gyrus lateral nuclear group of thalamus postcentral gyrus cerebellar hemisphere right hemisphere of cerebellum orbitofrontal cortex Top expressed in central gray substance of midbrain nucleus of stria terminalis paraventricular nucleus of hypothalamus superior colliculus arcuate nucleus dorsomedial hypothalamic nucleus median eminence suprachiasmatic nucleus habenula ventromedial nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytoplasm cytosol Biological process G protein-coupled receptor catabolic process endosome to lysosome transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9737 67298 Ensembl ENSG00000198932 ENSMUSG00000043384 UniProt Q5JY77 Q5U4C1 RefSeq (mRNA) NM_014710 NM_001099410 NM_001099411 NM_001184727 NM_001004359 NM_001005385 NM_026081 RefSeq (protein) NP_001092880 NP_001092881 NP_001171656 NP_055525 NP_001004359 NP_001005385 NP_080357 Location (UCSC) Chr X: 102.65 – 102.66 Mb Chr X: 134.64 – 134.7 Mb PubMed search
Wikidata
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G-protein coupled receptor-associated sorting protein 1 is a protein that in humans is encoded by the GPRASP1 gene.

Interactions

GPRASP1 (gene) has been shown to interact with Delta Opioid receptor.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000198932 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000043384 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Ishikawa K, Nagase T, Nakajima D, Seki N, Ohira M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (October 1997). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 4 (5): 307–13. doi:10.1093/dnares/4.5.307. PMID 9455477.
6. Simonin F, Karcher P, Boeuf JJ, Matifas A, Kieffer BL (May 2004). "Identification of a novel family of G protein-coupled receptor associated sorting proteins". Journal of Neurochemistry. 89 (3): 766–75. doi:10.1111/j.1471-4159.2004.02411.x. PMID 15086532. S2CID 6266231.
7. "Entrez Gene: GPRASP1 G protein-coupled receptor associated sorting protein 1".
8. Whistler JL, Enquist J, Marley A, Fong J, Gladher F, Tsuruda P, Murray SR, Von Zastrow M (July 2002). "Modulation of postendocytic sorting of G protein-coupled receptors". Science. 297 (5581): 615–20. doi:10.1126/science.1073308. PMID 12142540. S2CID 1219372.

Further reading

• Patrie KM, Drescher AJ, Goyal M, Wiggins RC, Margolis B (April 2001). "The membrane-associated guanylate kinase protein MAGI-1 binds megalin and is present in glomerular podocytes". Journal of the American Society of Nephrology. 12 (4): 667–77. doi:10.1681/ASN.V124667. PMID 11274227.
• Whistler JL, Enquist J, Marley A, Fong J, Gladher F, Tsuruda P, Murray SR, Von Zastrow M (July 2002). "Modulation of postendocytic sorting of G protein-coupled receptors". Science. 297 (5581): 615–20. doi:10.1126/science.1073308. PMID 12142540. S2CID 1219372.
• Heydorn A, Søndergaard BP, Ersbøll B, Holst B, Nielsen FC, Haft CR, Whistler J, Schwartz TW (December 2004). "A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated sorting protein (GASP)". The Journal of Biological Chemistry. 279 (52): 54291–303. doi:10.1074/jbc.M406169200. PMID 15452121.
• Bartlett SE, Enquist J, Hopf FW, Lee JH, Gladher F, Kharazia V, Waldhoer M, Mailliard WS, Armstrong R, Bonci A, Whistler JL (August 2005). "Dopamine responsiveness is regulated by targeted sorting of D2 receptors". Proceedings of the National Academy of Sciences of the United States of America. 102 (32): 11521–6. Bibcode:2005PNAS..10211521B. doi:10.1073/pnas.0502418102. PMC 1183554. PMID 16049099.
• Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (January 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

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