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Germacrone

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Germacrone
Names
Preferred IUPAC name (3E,7E)-3,7-Dimethyl-10-(propan-2-ylidene)cyclodeca-3,7-dien-1-one
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChemSpider
EC Number
  • 834-535-3
KEGG
PubChem CID
UNII
InChI
  • InChI=1S/C15H22O/c1-11(2)14-9-8-12(3)6-5-7-13(4)10-15(14)16/h7-8H,5-6,9-10H2,1-4H3/b12-8+,13-7+Key: CAULGCQHVOVVRN-SWZPTJTJSA-N
SMILES
  • C/C/1=C\CC(=C(C)C)C(=O)C/C(=C/CC1)/C
Properties
Chemical formula C15H22O
Molar mass 218.340 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

Germacrone is a sesquiterpene which has been isolated from Geranium macrorrhizum. It has shown antiviral properties in an animal model of influenza infection.

References

  1. Radulović, Niko S.; Dekić, Milan S.; Stojanović-Radić, Zorica Z.; Zoranić, Suad K. (2010). "Geranium macrorrhizum L. (Geraniaceae) essential oil: a potent agent against Bacillus subtilis". Chemistry & Biodiversity. 7 (11): 2783–800. doi:10.1002/cbdv.201000100. PMID 21072778. S2CID 7366166.
  2. Liao, Q; Qian, Z; Liu, R; An, L; Chen, X (2013). "Germacrone inhibits early stages of influenza virus infection". Antiviral Research. 100 (3): 578–88. doi:10.1016/j.antiviral.2013.09.021. PMID 24095670.


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