Misplaced Pages

Girolline

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
Girolline
Names
IUPAC name (1S,2S)-3-Amino-1-(2-amino-1H-imidazol-5-yl)-2-chloropropan-1-ol
Other names Giracodazole
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C6H11ClN4O/c7-3(1-8)5(12)4-2-10-6(9)11-4/h2-3,5,12H,1,8H2,(H3,9,10,11)/t3-,5+/m0/s1Key: YILCGOCHVFQMTC-WVZVXSGGSA-N
SMILES
  • ((CN)Cl)(O)C=1NC(N)=NC1
Properties
Chemical formula C6H11ClN4O
Molar mass 190.63 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

Girolline (also known as giracodazole) is a chemical compound isolated from a marine sponge. It inhibits protein synthesis.

References

  1. Fung, S. Y.; Sofiyev, V.; Schneiderman, J.; Hirschfeld, A. F.; Victor, R. E.; Woods, K.; Piotrowski, J. S.; Deshpande, R.; Li, S. C.; De Voogd, N. J.; Myers, C. L.; Boone, C.; Andersen, R. J.; Turvey, S. E. (2014). "Unbiased Screening of Marine Sponge Extracts for Anti-inflammatory Agents Combined with Chemical Genomics Identifies Girolline as an Inhibitor of Protein Synthesis". ACS Chemical Biology. 9 (1): 247–257. doi:10.1021/cb400740c. PMC 4371607. PMID 24117378.


Stub icon

This article about an organic compound is a stub. You can help Misplaced Pages by expanding it.

Categories: