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Glutaconate CoA-transferase

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Class of enzymes
glutaconate CoA-transferase
Identifiers
EC no.2.8.3.12
CAS no.79078-99-2
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IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
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In enzymology, a glutaconate CoA-transferase (EC 2.8.3.12) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + (E)-glutaconate {\displaystyle \rightleftharpoons } acetate + glutaconyl-1-CoA

Thus, the two substrates of this enzyme are acetyl-CoA and (E)-glutaconate, whereas its two products are acetate and glutaconyl-1-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is acetyl-CoA:(E)-glutaconate CoA-transferase. This enzyme participates in styrene degradation and butanoate metabolism.

References

Transferases: sulfur-containing group (EC 2.8)
2.8.1: Sulfurtransferases
2.8.2: Sulfotransferases
2.8.3: CoA-transferases
2.8.4: Alkylthio2.8.4:
2.8.5:2.8.5:
  • S-sulfo-L-cysteine synthase (3-phospho-L-serine-dependent) (*)
  • L-cysteine S-thiosulfotransferase (*)
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