Grodner is a surname meaning "someone from the city ofGrodno", in Belarus. Notable people with the surname include:
- Allison Grodner, American director, producer and writer
- Annetta Grodner, Ukrainian Jewish singer and actress, the first prima donna in Yiddish theater
- Israel Grodner (1848–1887), one of the founding performers in Yiddish theater
- Nahum Grodner (1811–1879), preacher and philanthropist
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