HCU may refer to:
Universities
- Heritage Christian University, in Florence, Alabama, United States
- Hiroshima City University, in Japan
- Houston Christian University, in Texas, United States
- Hsuan Chuang University, in Hsinchu City, Taiwan
- Huachiew Chalermprakiet University, in Samut Prakan, Thailand
- Hyderabad Central University, in India
Other uses
- Heavy Conversion Unit, of the Royal Air Force
- Homocystinuria
- Hyundai Chungun High School, in Dong-gu, Ulsan, South Korea
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