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HPH-15 is an antifibrotic drug with higher AMPK-activation activity than metformin.
References
- Toma, Tsugumasa; Miyakawa, Nobukazu; Arakaki, Yuiichi; Watanabe, Takuro; Nakahara, Ryosei; Ali, Taha F. S.; Biswas, Tanima; Todaka, Mikio; Kondo, Tatsuya; Fujita, Mikako; Otsuka, Masami; Araki, Eiichi; Tateishi, Hiroshi (2024). "An antifibrotic compound that ameliorates hyperglycaemia and fat accumulation in cell and HFD mouse models". Diabetologia. 67 (11): 2568–2584. doi:10.1007/s00125-024-06260-y. PMID 39251430.