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Haplogroup O (mtDNA)

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Human mitochondrial DNA haplogroup This article is about the human mtDNA haplogroup. For the human Y-DNA haplogroup, see Haplogroup O-M175.

Haplogroup O mtDNA is a haplogroup derived from haplogroup N and found in Oceania. Specifically, it is found among Aboriginal Australians. Its defining mutations are G6755A, C9140T, and G16213A.

It is one of the rarest haplogroups. As of 2022, FamilyTreeDNA reports that only 4 people in their customer base who have tested their complete mitochondrial sequences are members of the haplogroup. YFull reports 9 known members, 8 of whom are stated to be from Australia, and that the haplogroup is at least 20,000 years old.

The following table lists relevant GenBank samples:

Phylotree Haplogroup YFull Haplogroup GenBank ID Alternate ID State/Region
O O-a1 KY595606 AUS41 Queensland
O O-a1a AY289059 Aus23 Northern Territory
O O-a1a KY595554 AUS39 Queensland
O O-a1a KY595619 AUS40 Queensland
O1 O-a2 KY595668 AUS38 Queensland
O1 O1 DQ404447 AUD38 Northern Territory desert
O1a O1a AY289056 Aus20 Northern Territory
O1a O1a AY289058 Aus22 Northern Territory

Subclades

Tree

  • O
    • Oa1
      • Oa1a
    • O1
      • Oa2
    • O1
      • O1a

Notes

  1. Malliya (2004). "Phylogeny of Mitochondrial DNA Macrohaplogroup N in India, Based on Complete Sequencing: Implications for the Peopling of South Asia". The American Journal of Human Genetics. 75 (6): 966–978. doi:10.1086/425871. PMC 1182158. PMID 15467980.
  2. van Holst Pellekaan, Sheila M.; Ingman, Max; Roberts-Thomson, June; Harding, Rosalind M. (October 2006). "Mitochondrial genomics identifies major haplogroups in Aboriginal Australians". American Journal of Biological Anthropology. 131 (2): 282–294. doi:10.1002/ajpa.20426. PMID 16596590.
  3. Rasmussen, Morten; Guo, Xiaosen; Wang, Yong; Lohmueller, Kirk E.; Rasmussen, Simon; Albrechtsen, Anders; Skotte, Line; Lindgreen, Stinus; et al. (2011-10-07). "An Aboriginal Australian Genome Reveals Separate Human Dispersals into Asia". Science. 334 (6052): 94–98. doi:10.1126/science.1211177. hdl:10072/43493. PMID 21940856.
  4. "PhyloTree.org - mtDNA tree Build 17 (18 Feb 2016): subtree N".
  5. "Haplotree". Retrieved 30 August 2022.
  6. "O MTree". Retrieved 30 March 2024.
  7. ^ Nagle, Nano; van Oven, Mannis; Wilcox, Stephen; van Holst Pellekaan, Sheila; Tyler-Smith, Chris; Xue, Yali; Ballantyne, Kaye N.; Wilcox, Leah; Papac, Luka; Cooke, Karen; van Oorschot, Roland A. H.; McAllister, Peter; Williams, Lesley; Kayser, Manfred; Mitchell, R. John (2017-03-13). "Aboriginal Australian mitochondrial genome variation – an increased understanding of population antiquity and diversity". Scientific Reports. 7: Supplementary Figure 2. doi:10.1038/srep43041. PMC 5347126. PMID 28287095.

See also

Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups

  Mitochondrial Eve (L)    
L0 L1–6  
L1 L2   L3     L4 L5 L6
M N  
CZ D E G Q   O A S R   I W X Y
C Z B F R0   pre-JT   P   U
HV JT K
H V J T
Category: