Heinecke is a German surname. Notable people with the surname include:
- Andreas Heinecke, German academic and activist
- Birgit Heinecke (born 1957), East German handball player
- Herman Heinecke (1869-1906), American politician
- Kurt Heinecke, American composer
- William Heinecke (born 1949), American-born Thai businessman
See also
- Heinicke a similar surname
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