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Heme arginate

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Heme arginate
Identifiers
CAS Number
MeSH Heme+arginate
PubChem CID
UNII
Properties
Chemical formula C40H48FeN8O6
Molar mass 792.704
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒N verify (what is  ?) Infobox references
Chemical compound

Heme arginate (or haem arginate) is a compound of heme and arginine used in the treatment of acute porphyrias. This heme product is only available outside the United States and is equivalent to hematin.

Heme arginate is a heme compound, whereby L-arginine is added to prevent rapid degradation. It is given intravenously, and its action of mechanism is to reduce the overproduction of δ-aminolevulinic acid, which can cause the acute symptoms in an attack of the acute porphyrias.

See also

References

  1. "HAEM ARGINATE FOR THE ACUTE ATTACK OF PORPHYRIA". Porphyria South Africa. Archived from the original on 2012-03-05.
  2. "Treatment of the Acute Attack". European Porphyria Network. Archived from the original on 5 October 2011. Retrieved 28 August 2011.
  3. "Panhematin for Acute Porphyria". American Porphyria Foundation. Archived from the original on 12 March 2018. Retrieved 8 July 2016.
  4. Volin, L; V Rasi; E Vahtera; R Tenhunen (1988). "Heme arginate: effects on hemostasis" (PDF). Blood. 71 (3): 625–628. doi:10.1182/blood.V71.3.625.625. PMID 3345341. Retrieved 28 August 2011.
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