Hountondji is a surname. Notable people with the surname include:
- Andréas Hountondji (born 2002), French footballer
- Cédric Hountondji (born 1994), French footballer
- Gisèle Hountondji (born 1954), Beninese writer, interpreter, and translator
- Paulin J. Hountondji (born 1942), Beninese philosopher and politician
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