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Hydroxystilbamidine

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Hydroxystilbamidine
Names
Preferred IUPAC name 4--3-hydroxybenzene-1-carboximidamide
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.007.102 Edit this at Wikidata
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C16H16N4O/c17-15(18)12-5-2-10(3-6-12)1-4-11-7-8-13(16(19)20)9-14(11)21/h1-9,21H,(H3,17,18)(H3,19,20)/b4-1+Key: TUESWZZJYCLFNL-DAFODLJHSA-N
  • InChI=1/C16H16N4O/c17-15(18)12-5-2-10(3-6-12)1-4-11-7-8-13(16(19)20)9-14(11)21/h1-9,21H,(H3,17,18)(H3,19,20)/b4-1+Key: TUESWZZJYCLFNL-DAFODLJHBK
SMILES
  • Oc2cc(ccc2/C=C/c1ccc(cc1)C(N)=N)C(N)=N
Properties
Chemical formula C16H16N4O
Molar mass 280.324 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒N verify (what is  ?) Infobox references
Chemical compound
PVH neurons of Long-Evans rat marked with fluoro-gold

Hydroxystilbamidine is a fluorescent dye that emits different frequencies of light when bound to DNA and RNA. It is used as a retrograde tracer for outlining neurons, and as a histochemical stain.

References

  1. Naumann, Thomas (2000). "Retrograde tracing with Fluoro-Gold: different methods of tracer detection at the ultrastructural level and neurodegenerative changes of back-filled neurons in long-term studies". Journal of Neuroscience Methods. 103 (1): 11–21. doi:10.1016/S0165-0270(00)00292-2. PMID 11074092. S2CID 24155326.
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