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Indolelactate dehydrogenase

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indolelactate dehydrogenase
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EC no.1.1.1.110
CAS no.37250-41-2
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In enzymology, an indolelactate dehydrogenase (EC 1.1.1.110) is an enzyme that catalyzes the chemical reaction

(indol-3-yl)lactate + NAD {\displaystyle \rightleftharpoons } (indol-3-yl)pyruvate + NADH + H

Thus, the two substrates of this enzyme are (indol-3-yl)lactate and NAD, whereas its 3 products are (indol-3-yl)pyruvate, NADH, and H.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is (indol-3-yl)lactate:NAD oxidoreductase. This enzyme is also called indolelactate:NAD oxidoreductase. This enzyme participates in tryptophan metabolism.

References

  • Jean M, DeMoss RD (1968). "Indolelactate dehydrogenase from Clostridium sporogenes". Can. J. Microbiol. 14 (4): 429–35. doi:10.1139/m68-068. PMID 4384683.
Oxidoreductases: alcohol oxidoreductases (EC 1.1)
1.1.1: NAD/NADP acceptor
1.1.2: cytochrome acceptor
1.1.3: oxygen acceptor
1.1.4: disulfide as acceptor
1.1.5: quinone/similar acceptor
1.1.99: other acceptors
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