Janiszewski (feminine Janiszewska) is a Polish surname. Notable people with the surname include:
- Barbara Janiszewska (1936–2000), Polish athlete
- Henryk Janiszewski (born 1949), Polish ice hockey player
- Jerzy Janiszewski (born 1952), Polish artist
- Jill Janus (née Janiszewski; 1975–2018), American heavy metal singer
- Michał Janiszewski (1926–2016), Polish military officer
- Robert C. Janiszewski (born 1945), American politician
- Zygmunt Janiszewski (1888–1920), Polish mathematician
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