| Jeanette CrossleyMNZM | |
|---|---|
.jpg) | |
| Born | 1949 |
| Died | 11 October 2015 |
| Known for | developing blood spot tests for cystic fibrosis, Addison's disease research |
| Awards | Member of the New Zealand Order of Merit |
| Academic background | |
| Alma mater | University of Auckland |
| Thesis |
|
| Academic work | |
| Institutions | University of Auckland |
Jeanette Rosemary Crossley MNZM (nee Niblett, 1949 – 11 October 2015) was a New Zealand biochemist, who pioneered the development of bloodspot tests for the diagnosis of cystic fibrosis. In 2009 Crossley was appointed a Member of the New Zealand Order of Merit for services to science, in particular Addison's disease.
Academic career
Crossley completed a PhD titled The nature of urinary insulin in normal and diabetic subjects at the University of Auckland in 1973. Crossley worked for DSIR and then with Bob Elliott and P. A. Smith in the paediatrics department of the University of Auckland, where she developed a test for elevated trypsin levels in newborns using blood spots. This enabled nationwide screening of newborns and early diagnosis of cystic fibrosis, allowing earlier treatment and subsequent improvements in prognosis.
Crossley developed the New Zealand Addison's Network, a support network for New Zealanders with Addison's disease. She created a website and a newsletter issued three times a year, providing support for those with the disease. She also worked in paediatric diabetes research and was on the executive committee of the New Zealand Society for the Study of Diabetes.
In 1992 Crossley published a book about Matt Burke, a shepherd who worked on Ngamatea and Timahanga Stations.
Honours and awards
In the 2009 New Year Honours Crossley was appointed a Member of the New Zealand Order of Merit for services to science, in particular Addison's disease.
Personal life
Crossley was born in 1949, the only child of Eunice and Ernest Niblett. Crossley had Addison's disease and related autoimmune conditions, which restricted her life, and eventually led to her being bedridden. Crossley died in 2015 aged 66 years. She left a significant bequest to the University of Auckland, and funded research on loneliness in people with chronic and long-term illness.
Selected works
Scholia has a profile for Jeanette Rosemary Crossley (Q126793986).
- J. R. Crossley; R. B. Elliott; P. A. Smith (1 March 1979). "Dried-blood spot screening for cystic fibrosis in the newborn". The Lancet. 1 (8114): 472–474. doi:10.1016/S0140-6736(79)90825-0. ISSN 0140-6736. PMID 85057. Wikidata Q39534705.
- R B Elliott; J R Crossley; C C Berryman; A G James (1 July 1981). "Partial preservation of pancreatic beta-cell function in children with diabetes". The Lancet. 2 (8236): 1–4. doi:10.1016/S0140-6736(81)90249-X. ISSN 0140-6736. PMID 6113394. Wikidata Q72477079.
- S. J. Ashcroft; J. R. Crossley (1 August 1975). "The effects of glucose, N-acetylglucosamine, glyceraldehyde and other sugars on insulin release in vivo" (PDF). Diabetologia. 11 (4): 279–284. doi:10.1007/BF00422392. ISSN 0012-186X. PMID 1205021. Wikidata Q67355004.
- J R Crossley; M Upsdell (1 January 1980). "The incidence of juvenile diabetes mellitus in New Zealand". Diabetologia. 18 (1): 29–34. doi:10.1007/BF01228298. ISSN 0012-186X. PMID 7364162. Wikidata Q50592819.
- J R Crossley; P A Smith; B W Edgar; P D Gluckman; R B Elliott (1 June 1981). "Neonatal screening for cystic fibrosis, using immunoreactive trypsin assay in dried blood spots". Clinica Chimica Acta. 113 (2): 111–121. doi:10.1016/0009-8981(81)90145-5. ISSN 0009-8981. PMID 7249357. Wikidata Q70823208.
- S Serjeantson; J Theophilus; P Zimmet; J Court; J R Crossley; R B Elliott (1 January 1981). "Lymphocytotoxic antibodies and histocompatibility antigens in juvenile-onset diabetes mellitus". Diabetes. 30 (1): 26–29. doi:10.2337/DIAB.30.1.26. ISSN 0012-1797. PMID 7014302. Wikidata Q67301249.
- J. P. Palmer; M. K. Cooney; R. H. Ward; et al. (June 1982). "Reduced Coxsackie antibody titres in type 1 (insulin-dependent) diabetic patients presenting during an outbreak of Coxsackie B3 and B4 infection" (PDF). Diabetologia. 22 (6): 426–9. doi:10.1007/BF00282584. ISSN 0012-186X. PMID 6286394. Wikidata Q57114796.
References
- Crossley, Jeanette R. (1973). The nature of urinary insulin in normal and diabetic subjects (PhD thesis). University of Auckland.
- CFM. "Seventies clinical". Cystic Fibrosis Medicine. Retrieved 6 December 2024.
- ^ "Investitures - Auckland, The Governor-General of New Zealand". gg.govt.nz. Retrieved 6 December 2024.
- Navarro, Salvador (1 January 2016). "Historical compilation of cystic fibrosis". Gastroenterología y Hepatología (English Edition). 39 (1): 36–42. doi:10.1016/j.gastre.2015.12.006. ISSN 2444-3824.
- Trouvé, Pascal; Saint Pierre, Aude; Férec, Claude (January 2024). "Cystic Fibrosis: A Journey through Time and Hope". International Journal of Molecular Sciences. 25 (17): 9599. doi:10.3390/ijms25179599. ISSN 1422-0067. PMC 11394767. PMID 39273547.
- "Matt's Last Muster – A Shepherd's Journey". knowledgebank.org.nz. Retrieved 6 December 2024.
- ^ "Jeanette CROSSLEY Obituary (2015) - Auckland, Wellington - The New Zealand Herald". Legacy.com. Retrieved 6 December 2024.
- ^ "Bequest furthers understanding of social challenge - AUT". www.aut.ac.nz. Retrieved 6 December 2024.
- "The Chancellor's Circle - The University of Auckland". www.auckland.ac.nz. Retrieved 6 December 2024.
External links
- "Mega papers" in cystic fibrosis research, a summary of important papers in the field of diagnosis and treatment of cystic fibrosis