John Isham may refer to:
- Sir John Isham (1582–1651), High Sheriff of Northamptonshire
- John Isham (composer) (1680–1726), English composer and organist
- John Isham Farmstead, on the National Register of Historic Places listings in Lucas County, Ohio
- John William Isham (1866–?), American vaudeville impresario
Topics referred to by the same termThis disambiguation page lists articles about people with the same name. If an internal link led you here, you may wish to change the link to point directly to the intended article. Category: