José María Velasco may refer to:
- José María Velasco Gómez (1840–1912), Mexican painter
- José María Velasco Ibarra (1893–1979), president of Ecuador
- Temascalcingo, officially Temascalcingo de José María Velasco, a municipality in the State of Mexico
- José María Velasco (Mexico City Metrobús), a BRT station in Mexico City
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