Kaiko may refer to:
Geography
- Kaiko (mountain), a mountain in the Vilcabamba mountain range in the Andes of Peru.
People
- Takeshi Kaikō (1930-1989) prominent Japanese novelist
- Kaiko, brother of Kaukuna Kahekili, Hawaii
Other
- Kaiko GmbH video game development company located in Frankfurt, Germany
- Kaikō ROV (海溝, "Ocean Trench") remotely operated underwater vehicle (ROV) built by the Japan Agency for Marine-Earth Science and Technology (JAMSTEC)
- Kaiko (ship) Kaikō Maru, spotter ship for the Japanese whaling fleet circa 2007
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