Kilbirnie is a town in Ayrshire, Scotland. Kilbirnie may also refer to:
Australia
- Kilbirnie, Queensland, a locality in the Toowoomba Region, Australia
New Zealand
- Kilbirnie, New Zealand, a suburb of Wellington
Scotland
- Kilbirnie Loch, a freshwater lake
- Kilbirnie railway station, a former railway station
- Kilbirnie South railway station, a former railway station
- Barony and Castle of Kilbirnie, remains of an old castle
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