L'Hommedieu may refer to:
L'Hommedieu (surname)
- Ezra L'Hommedieu (1734–1811), American lawyer and politician
- Stephen S. L'Hommedieu (1806–1875), American newspaper publisher and railroad executive
- Wallace L'Hommedieu (1833–1916), American politician
- Irving L'Hommedieu (1865–1931), American lawyer and politician
L'Hommedieu (middle name)
- Stephen L'Hommedieu Slocum (1859–1933), American military attaché
- Tillinghast L'Hommedieu Huston (1867–1938), American civil engineer and baseball team owner
- Colden L'Hommedieu Ruggles (1869–1933), American general
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