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This is the list of Schedule II controlled substances in the United States as defined by the Controlled Substances Act. The following findings are required, by section 202 of that Act, for substances to be placed in this schedule:

1. The drug or other substance has a high potential for abuse.
2. The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions.
3. Abuse of the drug or other substances may lead to severe psychological or physical dependence.

The complete list of Schedule II substances is as follows. The Administrative Controlled Substances Code Number and Federal Register citation for each substance is included.

Drugs

See also

• List of Schedule I controlled substances (U.S.)
• List of Schedule III controlled substances (U.S.)
• List of Schedule IV controlled substances (U.S.)
• List of Schedule V controlled substances (U.S.)

Notes

1. ^ This substance was expressly scheduled by the Controlled Substances Act on October 27, 1970. The 1974 Federal Register ruling (by Administrator John R. Bartels, Jr.) merely organized its listing in the Code of Federal Regulations.

References

1. "21 C.F.R. 1308.12 (Schedule II)". Code of Federal Regulations. Retrieved September 7, 2023.
2. ^ Ingersoll, John (September 29, 1971). "Schedules of Controlled Substances: Removal of Naloxone From Control" (PDF). Isomer Design. Bureau of Narcotics and Dangerous Drugs. Archived from the original (PDF) on September 16, 2021. Retrieved September 7, 2023.
3. Mercado, Julio (November 17, 2000). "Schedule II Control of Dihydroetorphine Under the Controlled Substances Act". Federal Register. Drug Enforcement Administration. Retrieved September 7, 2023.
4. Bartels, Jr., John R. (March 29, 1974). "Etorphine Hydrochloride Transfer to Schedule II" (PDF). Isomer Design. Drug Enforcement Administration. Archived from the original (PDF) on September 26, 2021. Retrieved September 7, 2023.
5. Dhillon, Uttam (August 16, 2019). "Listing of Noroxymorphone in the Code of Federal Regulations and Assignment of a Controlled Substances Code Number". Federal Register. Drug Enforcement Administration. Retrieved September 7, 2023.
6. Leonhart, Michele (September 24, 2007). "Designation of Oripavine as a Basic Class of Controlled Substance". Federal Register. Drug Enforcement Administration. Retrieved September 7, 2023.
7. ^ Bartels Jr., John R. (June 20, 1974). "PART 1308— SCHEDULES OF CONTROLLED SUBSTANCES: Annual Publication" (PDF). Government Publishing Office. Drug Enforcement Administration. Archived from the original (PDF) on September 6, 2023. Retrieved September 6, 2023.
8. Bartels, Jr., John R. (February 14, 1975). "Concentrate of Poppy Straw, Addition to Schedule II and Authorizing its Importation" (PDF). Isomer Design. Drug Enforcement Administration. Archived from the original (PDF) on September 26, 2021. Retrieved September 7, 2023.
9. Lawn, John (January 23, 1987). "Rescheduling of Alfentanil from Schedule I to Schedule II" (PDF). Isomer Design. Drug Enforcement Administration. Archived from the original (PDF) on July 28, 2019. Retrieved September 7, 2023.
10. Bensinger, Peter (July 22, 1980). "Control of Bulk Dextropropoxyphene (Non-dosage Forms) in Schedule II as an Opiate" (PDF). Isomer Design. Drug Enforcement Administration. Archived from the original (PDF) on March 24, 2016. Retrieved September 7, 2023.
11. Lawn, John (October 28, 1988). "Placement of Carfentanil into Schedule II" (PDF). Isomer Design. Drug Enforcement Administration. Archived from the original (PDF) on March 22, 2016. Retrieved September 7, 2023.
12. Bonner, Robert (August 18, 1993). "Schedules of Controlled Substances; Transfer of Levo-acetylmethadol from Schedule I into Schedule II" (PDF). Isomer Design. Drug Enforcement Administration. Archived from the original (PDF) on July 28, 2019. Retrieved January 16, 2023.
13. Evans, D. Christopher (July 12, 2021). "Schedules of Controlled Substances: Placement of Oliceridine in Schedule II". Federal Register. Drug Enforcement Administration. Retrieved September 7, 2023.
14. Milford, Jr., James S. (November 5, 1996). "Schedules of Controlled Substances: Placement of Remifentanil Into Schedule II". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
15. Mullen, Jr., Francis M. (May 25, 1984). "Schedules of Controlled Substances; Rescheduling of Sufentanil into Schedule II" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on May 19, 2019. Retrieved January 16, 2023.
16. Leonhart, Michele (May 21, 2009). "Schedules of Controlled Substances: Placement of Tapentadol Into Schedule II". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
17. Dhillon, Uttam (June 10, 2019). "Schedules of Controlled Substances: Placement of Thiafentanil in Schedule II". Federal Register. Drug Enforcement Administration. Retrieved September 7, 2023.
18. ^ Ingersoll, John (July 7, 1971). "Amphetamine, Methamphetamine, and Optical Isomers" (PDF). Isomer Design. Bureau of Narcotics and Dangerous Drugs. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
19. ^ Finlator, John (October 28, 1971). "Phenmetrazine and its salts, and Methylphenidate" (PDF). Isomer Design. Bureau of Narcotics and Dangerous Drugs. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
20. Leonhart, Michele (May 3, 2007). "Schedules of Controlled Substances: Placement of Lisdexamfetamine Into Schedule II". Federal Register. Drug Enforcement Administration. Archived from the original on January 16, 2023. Retrieved January 16, 2023.
21. ^ Bartels, Jr., John R. (November 13, 1973). "Schedule II Control of Amobarbital, Pentobarbital, Secobarbital, and their salts" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
22. Bonner, Robert (March 21, 1991). "Schedules of Controlled Substances: Transfer of Glutethimide from Schedule III to Schedule II" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
23. Bensinger, Peter (January 25, 1978). "Placement of Phencyclidine in Schedule II" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
24. Lawn, John (April 7, 1987). "Placement of Nabilone in Schedule II" (PDF). Government Publishing Office. Drug Enforcement Administration. p. 11042. Archived from the original (PDF) on April 30, 2023. Retrieved September 7, 2023.
25. Patterson, Robert (November 22, 2017). "Schedules of Controlled Substances: Placement of FDA-Approved Products of Oral Solutions Containing Dronabinol [(-)-delta-9-trans-tetrahydrocannabinol (delta-9-THC)] in Schedule II". Federal Register. Drug Enforcement Administration. Retrieved September 7, 2023.
26. ^ Bensinger, Peter (February 11, 1980). "Schedules of Controlled Substances; Schedule II Placement of Phenylacetone; (Phenyl-2-propanone, P2P, methyl benzyl ketone, benzyl methyl ketone)" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
27. Leonhart, Michele (June 29, 2010). "Control of Immediate Precursor Used in the Illicit Manufacture of Fentanyl as a Schedule II Controlled Substance". Federal Register. Drug Enforcement Administration. Archived from the original on January 16, 2023. Retrieved January 16, 2023.
28. Dhillon, Uttam (April 17, 2020). "Control of the Immediate Precursor Norfentanyl Used in the Illicit Manufacture of Fentanyl as a Schedule II Controlled Substance". Federal Register. Drug Enforcement Administration. Retrieved September 7, 2023.

• Controlled Substances Act
• Drug-related lists