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MC21-B

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MC21-B
Names
Preferred IUPAC name 2,2′,3-Tribromo-4,4′-dicarboxylic acid
Other names 2,2′,3-Tribromobiphenyl-4,4′-dicarboxylic acid
Identifiers
3D model (JSmol)
PubChem CID
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C14H7Br3O4/c15-10-5-6(13(18)19)1-2-7(10)8-3-4-9(14(20)21)12(17)11(8)16/h1-5H,(H,18,19)(H,20,21)Key: BTFCVLPFWWMQRI-UHFFFAOYSA-N
SMILES
  • OC(=O)c1cc(Br)c(cc1)c2c(Br)c(Br)c(cc2)C(=O)O
Properties
Chemical formula C14H7Br3O4
Molar mass 478.918 g·mol
Appearance White powder
Solubility in water Sol. MeOH, CHCl3
insol. H2O, hexane
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

MC21-B is an antibiotic isolated from the O-BC30T strain of a marine bacterium, Pseudoalteromonas phenolica. MC21-B is cytotoxic to human leukaemia cells and human normal dermal fibroblasts.

See also

References

  1. Isnansetyo, A.; Kamei, Y. (2009). "Anti-methicillin-resistant Staphylococcus aureus (MRSA) activity of MC21-B, an antibacterial compound produced by the marine bacterium Pseudoalteromonas phenolica O-BC30T". International Journal of Antimicrobial Agents. 34 (2): 131–135. doi:10.1016/j.ijantimicag.2009.02.009. PMID 19329285.
  2. Rahman, H.; Austin, B.; Mitchell, W. J.; Morris, P. C.; Jamieson, D. J.; Adams, D. R.; Spragg, A. M.; Schweizer, M. (2010). "Novel Anti-Infective Compounds from Marine Bacteria". Marine Drugs. 8 (3): 498–518. doi:10.3390/md8030498. PMC 2857357. PMID 20411112.


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