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MOWSE (for Molecular Weight Search) is a method to identify proteins from the molecular weight of peptides created by proteolytic digestion and measured with mass spectrometry.
Development
The MOWSE algorithm was developed by Darryl Pappin at the Imperial Cancer Research Fund and Alan Bleasby at the SERC Daresbury Laboratory. The probability-based MOWSE score formed the basis of development of Mascot, a proprietary software for protein identification from mass spectrometry data.
See also
References
- Pappin DJ, Hojrup P, Bleasby AJ (June 1993). "Rapid identification of proteins by peptide-mass fingerprinting". Curr. Biol. 3 (6): 327–32. doi:10.1016/0960-9822(93)90195-T. PMID 15335725. S2CID 40203243.
- "A history of Mascot and Mowse". www.matrixscience.com.
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