Major Thomas may refer to:
Last name
- Major James Francis Thomas (1861–1942), a soldier from New South Wales
- Major W. Ian Thomas (1914–2007), a Christian evangelical
First name
- Major Thomas Beckford (1618–1685), former Sheriff of London
- Major Thomas "Robin" Dixon (1935–), a former British bobsledder and Northern Irish politician
- Major Thomas "Harry" Gem (1819–1881), an English lawyer, soldier, writer, and sportsman
- Major Thomas D. Howie (1908–1944), a United States Army officer killed during the Battle of Normandy
- Major Thomas Jones (1665–1713), an influential figure on Long Island
- Major Thomas Lansdale (1748–1803), an American officer in the Revolutionary War
- Major Thomas Bleakley McDowell (1923–2009), former chief executive of The Irish Times
- Major Thomas McGuire (1920–1945), a U.S. Medal of Honor recipient killed in action during World War II
- Major Thomas McHugh (1919–2000), a United States Marine
- Major Thomas Mitchell (1792–1855), a surveyor and explorer of Southeastern Australia
- Major Thomas Freeman-Mitford (1909–1945), a British officer killed in action in Burma during World War II
- Major Thomas Orde-Lees (1877–1958), an Antarctic explorer, parachutist, and mountaineer
- Major Thomas Savage (1608–1682), a soldier during King Philip's War
- Major Thomas Vile (1882–1958), a Welsh international rugby union player
- Major Thomas Weir (1599–1670), an executed Scottish soldier and strict Presbyterian
See also
- Major Tom (disambiguation)
- Thomas Major (1720–1799), an English engraver
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