Margaret Scott or Maggie Scott may refer to:
- Margaret Scott (Salem witch trials) (c. 1615–1692), convicted at the Salem witch trials and hanged
- Lady Margaret Montagu Douglas Scott (1846–1918), Scottish aristocrat
- Lady Margaret Scott (golfer) (1874–1938), British golfer
- Margaret Scott (suffragette) or Margot Schenke (1888–1973), UK suffragette
- Margaret Scott (dancer) (1922–2019), South African-born Australian dancer
- Margaret Scott (New Zealand author) (1928–2014), New Zealand writer, editor and librarian
- Marilyn Waltz or Margaret Scott (1931–2006), American actress and model
- Margaret Scott (Australian author) (1934–2005), Australian author, poet and television personality
- Maggie Scott, Lady Scott (born 1960), member of the Scottish Faculty of Advocates and Queen's Counsel
- Maggie Scott (1955), British actor, feminist, textile artist and wife of actor Paul Freeman
- USS Margaret Scott, a U.S. Navy Stone Fleet ship
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