Metabutoxycaine - Misplaced Pages

Chemical compound Pharmaceutical compound

Metabutoxycaine
Clinical data

Routes of administration	Dental syringe (as novocaine is administered)
Pharmacokinetic data
Metabolism	Lasts for at least 12 hours after injection.
Identifiers
IUPAC name 2-diethylaminoethyl 3-amino-2-butoxybenzoate
CAS Number	3624-87-1
PubChem CID	19247
ChemSpider	18160
UNII	AMV9L2WT8K
CompTox Dashboard (EPA)	DTXSID40189787
Chemical and physical data
Formula	C₁₇H₂₈N₂O₃
Molar mass	308.422 g·mol
3D model (JSmol)	Interactive image
SMILES CCCCOC1=C(C=CC=C1N)C(=O)OCCN(CC)CC
InChI InChI=1S/C17H28N2O3/c1-4-7-12-21-16-14(9-8-10-15(16)18)17(20)22-13-11-19(5-2)6-3/h8-10H,4-7,11-13,18H2,1-3H3 Key:LJQWYEFHNLTPBZ-UHFFFAOYSA-N
(verify)

Metabutoxycaine, marketed under the trade name Primacaine, is a local anesthetic. It is used in dentistry. It has the U.S. patent number 2,882,296.

References

Wang HS, Gao MS, Li S (December 2003). "". Shanghai Kou Qiang Yi Xue = Shanghai Journal of Stomatology (in Chinese). 12 (6): 452, 459. PMID 14966589.
Raymond O Clinton, Stanley C Laskowski, U.S. patent 2,882,296 (1959 to Sterling Drug Inc).

Local anesthetics (primarily sodium channel blockers) (N01B)

Esters by acid

Aminobenzoic	Benzocaine Benzonatate Butacaine Butamben Chloroprocaine Dimethocaine Lucaine Meprylcaine Metabutethamine Metabutoxycaine Nitracaine Orthocaine Propoxycaine Procaine (Novocaine) Proxymetacaine Risocaine Tetracaine
Benzoic	Amylocaine Cocaine Cyclomethycaine α-Eucaine β-Eucaine Hexylcaine Isobucaine Piperocaine
ArCO2- (not para-amino or Ph)	Amoproxan (3,4,5-Trimethoxybenzoyl) 3-(p-Fluorobenzoyloxy)tropane

Amides

Combinations

WHO-EM
Withdrawn from market
Clinical trials:
- Phase III
- Never to phase III

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