Misplaced Pages

MicroRNA 548v

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
Non-coding RNA in the species Homo sapiens
MIR548V
Identifiers
AliasesMIR548V, microRNA 548v
External IDsGeneCards: MIR548V; OMA:MIR548V - orthologs
Gene location (Human)
Chromosome 8 (human)
Chr.Chromosome 8 (human)
Chromosome 8 (human)Genomic location for MIR548VGenomic location for MIR548V
Band8p22Start17,681,578 bp
End17,681,657 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • corpus callosum

  • sural nerve

  • Achilles tendon

  • appendix

  • duodenum

  • blood

  • liver

  • endometrium

  • placenta

  • human kidney
    n/a
More reference expression data
BioGPS
n/a
Orthologs
SpeciesHumanMouse
Entrez

100422850

n/a

Ensembl

ENSG00000265520

n/a

UniProt

n
a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)Chr 8: 17.68 – 17.68 Mbn/a
PubMed searchn/a
Wikidata
View/Edit Human

MicroRNA 548v is a protein that in humans is encoded by the MIR548V gene.

Function

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs.

miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products.

The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000265520 – Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Entrez Gene: MicroRNA 548v". Retrieved 2017-10-05.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


Stub icon

This article on a gene on human chromosome 8 is a stub. You can help Misplaced Pages by expanding it.

Categories: