Milius may refer to:
- USS Milius (DDG-69), missile destroyer of the United States Navy
- Pope Avilius of Alexandria, also known as Milius, Patriarch of Alexandria between 83 and 95
People with the surname
- Jeronimas Milius (born 1984), Lithuanian singer
- John Milius (born 1944), American screenwriter and director
Film
- Milius (film), a 2013 documentary about the filmmaker
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