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NAPB
Identifiers
Aliases	NAPB, SNAP-BETA, SNSF attachment protein beta
External IDs	OMIM: 611270; MGI: 104562; HomoloGene: 5332; GeneCards: NAPB; OMA:NAPB - orthologs
Gene location (Human) Chr. Chromosome 20 (human) Band 20p11.21 Start 23,374,519 bp End 23,421,519 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2|2 G3 Start 148,535,905 bp End 148,574,387 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in middle temporal gyrus Brodmann area 23 endothelial cell Pons superior frontal gyrus cerebellar vermis lateral nuclear group of thalamus pars compacta Parietal Lobe postcentral gyrus Top expressed in pontine nuclei subiculum anterior amygdaloid area habenula medial vestibular nucleus ventral tegmental area prefrontal cortex dorsal tegmental nucleus ventromedial nucleus dentate gyrus of hippocampal formation granule cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function syntaxin binding protein binding soluble NSF attachment protein activity Cellular component SNARE complex extracellular exosome membrane vacuolar membrane synaptobrevin 2-SNAP-25-syntaxin-1a complex Biological process protein transport SNARE complex disassembly membrane fusion intracellular protein transport vesicle-mediated transport transport regulation of synaptic vesicle priming synaptic transmission, glutamatergic Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 63908 17957 Ensembl ENSG00000125814 ENSMUSG00000027438 UniProt Q9H115 P28663 RefSeq (mRNA) NM_001283018 NM_001283020 NM_001283026 NM_022080 NM_019632 RefSeq (protein) NP_001269947 NP_001269949 NP_001269955 NP_071363 NP_062606 Location (UCSC) Chr 20: 23.37 – 23.42 Mb Chr 2: 148.54 – 148.57 Mb PubMed search
Wikidata
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Beta-soluble NSF attachment protein is a SNAP protein involved in vesicular trafficking and exocytosis which is encoded by the NAPB gene humans is.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000125814 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000027438 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Whiteheart SW, Griff IC, Brunner M, Clary DO, Mayer T, Buhrow SA, Rothman JE (Apr 1993). "SNAP family of NSF attachment proteins includes a brain-specific isoform". Nature. 362 (6418): 353–5. Bibcode:1993Natur.362..353W. doi:10.1038/362353a0. PMID 8455721. S2CID 4341471.
6. "Entrez Gene: NAPB N-ethylmaleimide-sensitive factor attachment protein, beta".

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
• Prekeris R, Klumperman J, Chen YA, Scheller RH (1998). "Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes". J. Cell Biol. 143 (4): 957–71. doi:10.1083/jcb.143.4.957. PMC 2132958. PMID 9817754.
• Osten P, Srivastava S, Inman GJ, et al. (1998). "The AMPA receptor GluR2 C terminus can mediate a reversible, ATP-dependent interaction with NSF and alpha- and beta-SNAPs". Neuron. 21 (1): 99–110. doi:10.1016/S0896-6273(00)80518-8. PMID 9697855. S2CID 18569829.
• Wilson DW, Whiteheart SW, Wiedmann M, et al. (1992). "A multisubunit particle implicated in membrane fusion". J. Cell Biol. 117 (3): 531–8. doi:10.1083/jcb.117.3.531. PMC 2289450. PMID 1315316.

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