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NOSIP
Identifiers
Aliases	NOSIP, CGI-25, nitric oxide synthase interacting protein
External IDs	OMIM: 616759; MGI: 1913644; HomoloGene: 9315; GeneCards: NOSIP; OMA:NOSIP - orthologs
Gene location (Human) Chr. Chromosome 19 (human) Band 19q13.33 Start 49,555,468 bp End 49,590,262 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 B3 Start 44,711,853 bp End 44,727,634 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left testis granulocyte right testis body of pancreas triceps brachii muscle muscle of thigh blood mucosa of transverse colon tendon of biceps brachii glutes Top expressed in spermatid spermatocyte interventricular septum lip blastocyst genital tubercle granulocyte otic vesicle epiblast neural layer of retina More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding transferase activity RNA binding ubiquitin protein ligase activity Cellular component cytoplasm cytosol Golgi membrane nucleus Biological process negative regulation of catalytic activity negative regulation of nitric-oxide synthase activity multicellular organism development protein ubiquitination regulation of nitric-oxide synthase activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51070 66394 Ensembl ENSG00000142546 ENSMUSG00000003421 UniProt Q9Y314 Q9D6T0 RefSeq (mRNA) NM_001270960 NM_015953 NM_001363649 NM_001163684 NM_025533 RefSeq (protein) NP_001257889 NP_057037 NP_001350578 NP_001157156 NP_079809 Location (UCSC) Chr 19: 49.56 – 49.59 Mb Chr 7: 44.71 – 44.73 Mb PubMed search
Wikidata
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Nitric oxide synthase-interacting protein is an enzyme that in humans is encoded by the NOSIP gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000142546 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000003421 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Dedio J, Konig P, Wohlfart P, Schroeder C, Kummer W, Muller-Esterl W (Jan 2001). "NOSIP, a novel modulator of endothelial nitric oxide synthase activity". FASEB J. 15 (1): 79–89. doi:10.1096/fj.00-0078com. PMID 11149895. S2CID 34485514.
6. Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
7. "Entrez Gene: NOSIP nitric oxide synthase interacting protein".

Further reading

• Schleicher M, Brundin F, Gross S, et al. (2005). "Cell cycle-regulated inactivation of endothelial NO synthase through NOSIP-dependent targeting to the cytoskeleton". Mol. Cell. Biol. 25 (18): 8251–8. doi:10.1128/MCB.25.18.8251-8258.2005. PMC 1234313. PMID 16135813.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
• Dreyer J, Schleicher M, Tappe A, et al. (2005). "Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity". J. Neurosci. 24 (46): 10454–65. doi:10.1523/JNEUROSCI.2265-04.2004. PMC 6730309. PMID 15548660.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

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