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Nifurtoinol

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Chemical compound Pharmaceutical compound
Nifurtoinol
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral
ATC code
Pharmacokinetic data
ExcretionRenal (40–50% within the first 12 hours)
Identifiers
IUPAC name
  • 3-(hydroxymethyl)-1-{amino}imidazolidine-2,4-dione
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
CompTox Dashboard (EPA)
ECHA InfoCard100.012.842 Edit this at Wikidata
Chemical and physical data
FormulaC9H8N4O6
Molar mass268.185 g·mol
3D model (JSmol)
SMILES
  • C1C(=O)N(C(=O)N1/N=C/C2=CC=C(O2)(=O))CO
InChI
  • InChI=1S/C9H8N4O6/c14-5-11-7(15)4-12(9(11)16)10-3-6-1-2-8(19-6)13(17)18/h1-3,14H,4-5H2/b10-3+
  • Key:UIDWQGRXEVDFCA-XCVCLJGOSA-N
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Nifurtoinol (rINN, trade name Urfadyn) is a nitrofuran-derivative antibiotic used in the treatment of urinary tract infections.

It is also known as "hydroxymethylnitrofurantoin".

References

  1. Stricker BH, Blok AP, Claas FH, Van Parys GE, Desmet VJ (1988). "Hepatic injury associated with the use of nitrofurans: a clinicopathological study of 52 reported cases". Hepatology. 8 (3): 599–606. doi:10.1002/hep.1840080327. PMID 3371877.
Antibacterials: others (J01X, D06AX)
Glycopeptides
Lipoglycopeptides
Polymyxins
Steroid antibacterials
Imidazole derivatives
Pleuromutilins
Nitrofuran derivatives
Other antibacterials


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