Misplaced Pages

Nucleoside oxidase (EC 1.1.3.28) is an enzyme with systematic name nucleoside:oxygen 5'-oxidoreductase. This enzyme catalyses the following chemical reaction

inosine + O₂ ${\displaystyle \rightleftharpoons }$ 9-riburonosylhypoxanthine + H₂O

(1a) 2 inosine + O₂ ${\displaystyle \rightleftharpoons }$ 2 5'-dehydroinosine + 2 H₂O

(1b) 2 5'-dehydroinosine + O₂ ${\displaystyle \rightleftharpoons }$ 2 9-riburonosylhypoxanthine

This enzyme could use other purine and pyrimidine nucleosides (as well as 2'-deoxynucleosides) as substrates.

References

1. Isono Y, Sudo T, Hoshino M (1989). "Purification and reaction of a new enzyme, nucleoside oxidase". Agric. Biol. Chem. 53: 1663–1669. doi:10.1271/bbb1961.53.1663.
2. Isono Y, Sudo T, Hoshino M (1989). "Properties of a new enzyme, nucleoside oxidase, from Pseudomonas maltophilia LB-86". Agric. Biol. Chem. 53: 1671–1677. doi:10.1271/bbb1961.53.1671.

External links

• Nucleoside+oxidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

• Biology

• EC 1.1.3