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NAP1L5
Identifiers
Aliases	NAP1L5, DRLM, nucleosome assembly protein 1 like 5
External IDs	OMIM: 612203; MGI: 1923555; HomoloGene: 36397; GeneCards: NAP1L5; OMA:NAP1L5 - orthologs
Gene location (Human) Chr. Chromosome 4 (human) Band 4q22.1|4q21-q22 Start 88,695,913 bp End 88,697,829 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band 6|6 B3 Start 58,882,218 bp End 58,884,061 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell Brodmann area 23 middle temporal gyrus lateral nuclear group of thalamus pars compacta Pons superior vestibular nucleus pars reticulata cerebellar vermis Brodmann area 46 Top expressed in dorsomedial hypothalamic nucleus paraventricular nucleus of hypothalamus lateral hypothalamus dorsal tegmental nucleus ventral tegmental area ventromedial nucleus mammillary body arcuate nucleus superior colliculus median eminence More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 266812 58243 Ensembl ENSG00000177432 ENSMUSG00000055430 UniProt Q96NT1 Q9JJF0 RefSeq (mRNA) NM_153757 NM_021432 RefSeq (protein) NP_715638 NP_067407 Location (UCSC) Chr 4: 88.7 – 88.7 Mb Chr 6: 58.88 – 58.88 Mb PubMed search
Wikidata
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Nucleosome assembly protein 1 like 5 is a protein that in humans is encoded by the NAP1L5 gene.

Function

This gene encodes a protein that shares sequence similarity to nucleosome assembly factors, but may be localized to the cytoplasm rather than the nucleus. Expression of this gene is downregulated in hepatocellular carcinomas. This gene is located within a differentially methylated region (DMR) and is imprinted and paternally expressed. There is a related pseudogene on chromosome 4. .

References

1. ^ GRCh38: Ensembl release 89: ENSG00000177432 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000055430 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Nucleosome assembly protein 1 like 5". Retrieved 2018-04-02.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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