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Olfactomedin 3

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(Redirected from OLFM3) Protein-coding gene in the species Homo sapiens
OLFM3
Identifiers
AliasesOLFM3, NOE3, NOELIN3, OPTIMEDIN, olfactomedin 3
External IDsOMIM: 607567; MGI: 2387329; HomoloGene: 17103; GeneCards: OLFM3; OMA:OLFM3 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)
Chromosome 1 (human)Genomic location for OLFM3Genomic location for OLFM3
Band1p21.1Start101,802,560 bp
End101,996,926 bp
Gene location (Mouse)
Chromosome 3 (mouse)
Chr.Chromosome 3 (mouse)
Chromosome 3 (mouse)Genomic location for OLFM3Genomic location for OLFM3
Band3|3 F3Start114,697,727 bp
End114,919,371 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • endothelial cell

  • Brodmann area 23

  • middle temporal gyrus

  • superior frontal gyrus

  • Brodmann area 46

  • prefrontal cortex

  • dorsolateral prefrontal cortex

  • Brodmann area 9

  • lateral nuclear group of thalamus

  • postcentral gyrus
Top expressed in
  • lobe of cerebellum

  • cerebellar vermis

  • habenula

  • olfactory tubercle

  • substantia nigra

  • medial geniculate nucleus

  • mammillary body

  • lateral geniculate nucleus

  • paraventricular nucleus of hypothalamus

  • superior colliculus
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

118427

229759

Ensembl

ENSG00000118733

ENSMUSG00000027965

UniProt

Q96PB7

P63056

RefSeq (mRNA)

NM_001288821
NM_001288823
NM_058170

NM_001286750
NM_153157
NM_153458

RefSeq (protein)

NP_001275750
NP_001275752
NP_477518

NP_001273679
NP_694797
NP_703188

Location (UCSC)Chr 1: 101.8 – 102 MbChr 3: 114.7 – 114.92 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Olfactomedin 3, also known as noelin 3 or optimedin, is a protein that in humans is encoded by the OLFM3 gene.

Interactions

OLFM3 has been shown to interact with MYOC.

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000118733Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000027965Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Torrado M, Trivedi R, Zinovieva R, Karavanova I, Tomarev SI (May 2002). "Optimedin: a novel olfactomedin-related protein that interacts with myocilin". Hum Mol Genet. 11 (11): 1291–301. doi:10.1093/hmg/11.11.1291. PMID 12019210.
  6. Grinchuk O, Kozmik Z, Wu X, Tomarev S (Oct 2005). "The Optimedin gene is a downstream target of Pax6". J Biol Chem. 280 (42): 35228–37. doi:10.1074/jbc.M506195200. PMID 16115881.
  7. "Entrez Gene: OLFM3 olfactomedin 3".

Further reading


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