Misplaced Pages

PPP1R14B
Identifiers
Aliases	PPP1R14B, PHI-1, PLCB3N, PNG, SOM172, protein phosphatase 1 regulatory inhibitor subunit 14B
External IDs	OMIM: 601140; MGI: 107682; HomoloGene: 7483; GeneCards: PPP1R14B; OMA:PPP1R14B - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11q13.1 Start 64,244,479 bp End 64,246,943 bp
Gene location (Mouse) Chr. Chromosome 19 (mouse) Band 19|19 A Start 6,952,336 bp End 6,954,692 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence body of pancreas right coronary artery stromal cell of endometrium apex of heart muscle of thigh mucosa of transverse colon skin of abdomen skin of leg gastrocnemius muscle Top expressed in ventricular zone lip esophagus yolk sac muscle of thigh nucleus pulposus zygote spermatid embryo embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein phosphatase inhibitor activity phosphatase inhibitor activity protein phosphatase regulator activity protein serine/threonine phosphatase inhibitor activity Cellular component cytoplasm Biological process regulation of phosphorylation innate immune response negative regulation of phosphoprotein phosphatase activity negative regulation of catalytic activity regulation of phosphoprotein phosphatase activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26472 18938 Ensembl ENSG00000173457 ENSMUSG00000056612 UniProt Q96C90 Q62084 RefSeq (mRNA) NM_138689 NM_008889 RefSeq (protein) NP_619634 NP_032915 Location (UCSC) Chr 11: 64.24 – 64.25 Mb Chr 19: 6.95 – 6.95 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Protein phosphatase 1 regulatory subunit 14B is an enzyme that in humans is encoded by the PPP1R14B gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000173457 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000056612 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Lagercrantz J, Carson E, Larsson C, Nordenskjold M, Weber G (Mar 1997). "Isolation and characterization of a novel gene close to the human phosphoinositide-specific phospholipase C beta 3 gene on chromosomal region 11q13". Genomics. 31 (3): 380–4. doi:10.1006/geno.1996.0063. PMID 8838322.
6. Eto M, Karginov A, Brautigan DL (Jan 2000). "A novel phosphoprotein inhibitor of protein type-1 phosphatase holoenzymes". Biochemistry. 38 (51): 16952–7. doi:10.1021/bi992030o. PMID 10606530.
7. "Entrez Gene: PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B".

Further reading

• Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. Bibcode:2000PNAS...97.3491D. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Tountas NA, Mandell JW, Everett AD, Brautigan DL (2005). "Juxtamembrane localization of the protein phosphatase-1 inhibitor protein PHI-1 in smooth muscle cells". Histochem. Cell Biol. 121 (4): 343–50. doi:10.1007/s00418-004-0642-8. PMID 15083373. S2CID 21262452.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Tountas NA, Brautigan DL (2005). "Migration and retraction of endothelial and epithelial cells require PHI-1, a specific protein-phosphatase-1 inhibitor protein". J. Cell Sci. 117 (Pt 24): 5905–12. doi:10.1242/jcs.01506. PMID 15522888. S2CID 2619985.
• Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.

This article on a gene on human chromosome 11 is a stub. You can help Misplaced Pages by expanding it.

• v
• t
• e

• Genes on human chromosome 11
• Human chromosome 11 gene stubs