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Medical intervention
Phemister graft
Illustration of an autograft harvested from iliac crest
A Phemister graft is a type of bone graft which uses bone tissue harvested from the patient to treat slow-healing, or delayed unionbone fractures. Thus, it is a form of autotransplantation. Typically, the tissue used in the graft is cancellous bone harvested from the patient's Iliac crest and laid in strips across the fracture site. The use of the patient's living bone stimulates osteogenesis, the growth of bones.
The Phemister graft is preferred when a fracture demonstrates delayed union, meaning the fracture is slow to heal. Due to internal forces, the procedure is not recommended for the femur, humerus, or radius bones. It can be used for areas of bone which have undergone the first two stages of osteonecrosis. For example, in young patients, or those with sickle cell disease, it can serve as an effective long-term treatment for osteonecrosis, as long as it is performed in the early stages. In this instances, it is a more conservative treatment, and in the long term can postpone the need for a hip replacement. In the later stages of osteonecrosis (3 through 6), where the bone has begun to collapse or has fully collapsed, the Phemister graft is not recommended.
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Wu, Cheng-Ta; Yen, Shih-Hsiang; Lin, Po-Chun; Wang, Jun-Wen (2018-06-18). "Long-term outcomes of Phemister bone grafting for patients with non-traumatic osteonecrosis of the femoral head". International Orthopaedics. 43 (3): 579–587. doi:10.1007/s00264-018-4013-9. ISSN0341-2695. PMID29916000. S2CID49300087.
Nelson, Lynn M; Clark, Charles R (1993-06-01). "Efficacy of phemister bone grafting in nontraumatic aseptic necrosis of the femoral head". The Journal of Arthroplasty. 8 (3): 253–258. doi:10.1016/S0883-5403(06)80086-0. ISSN0883-5403. PMID8326305.