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Phloroglucinol reductase

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Class of enzymes
phloroglucinol reductase
Identifiers
EC no.1.3.1.57
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In enzymology, a phloroglucinol reductase (EC 1.3.1.57) is an enzyme that catalyzes the chemical reaction

dihydrophloroglucinol + NADP {\displaystyle \rightleftharpoons } phloroglucinol + NADPH + H

Thus, the two substrates of this enzyme are dihydrophloroglucinol and NADP, whereas its 3 products are phloroglucinol, NADPH, and H.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is dihydrophloroglucinol:NADP+ oxidoreductase. This enzyme participates in benzoate degradation via coa ligation.

References

  • Haddock JD, Ferry JG (1989). "Purification and properties of phloroglucinol reductase from Eubacterium oxidoreducens G-41". J. Biol. Chem. 264 (8): 4423–7. PMID 2925649.
Oxidoreductases: CH–CH oxidoreductases (EC 1.3)
1.3.1: NAD/NADP acceptor
1.3.3: Oxygen acceptor
1.3.5: Quinone
1.3.99: Other acceptors
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