Misplaced Pages

Phosphatidylcholine—retinol O-acyltransferase

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
phosphatidylcholine-retinol O-acyltransferase
Identifiers
EC no.2.3.1.135
CAS no.117444-03-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a phosphatidylcholine---retinol O-acyltransferase (EC 2.3.1.135) is an enzyme that catalyzes the chemical reaction

phosphatidylcholine + retinol--- {\displaystyle \rightleftharpoons } 2-acylglycerophosphocholine + retinyl-ester---

Thus, the two substrates of this enzyme are phosphatidylcholine and ]], whereas its two products are 2-acylglycerophosphocholine and ]].

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is phosphatidylcholine:retinol--- O-acyltransferase. Other names in common use include lecithin---retinol acyltransferase, phosphatidylcholine:retinol-(cellular-retinol-binding-protein), and O-acyltransferase.

References

  • MacDonald PN, Ong DE (1988). "Evidence for a lecithin-retinol acyltransferase activity in the rat small intestine". J. Biol. Chem. 263 (25): 12478–82. PMID 3410848.
  • Saari JC, Bredberg DL (1989). "Lecithin:retinol acyltransferase in retinal pigment epithelial microsomes". J. Biol. Chem. 264 (15): 8636–40. PMID 2722792.
Transferases: acyltransferases (EC 2.3)
2.3.1: other than amino-acyl groups
2.3.2: Aminoacyltransferases
2.3.3: converted into alkyl on transfer
Enzymes
Activity
Regulation
Classification
Kinetics
Types
Portal:


This EC 2.3 enzyme-related article is a stub. You can help Misplaced Pages by expanding it.

Categories: