Proscillaridin - Misplaced Pages

(Redirected from Proscillaridine A) Chemical compound Pharmaceutical compound

Proscillaridin
Clinical data

Other names	14β-Hydroxy-3β-bufa-4,20,22-trienolide
AHFS/Drugs.com	International Drug Names
ATC code	C01AB01 (WHO)
Identifiers
IUPAC name 5-phenanthren-17-yl]-2H-pyran-2-one
CAS Number	466-06-8
PubChem CID	5284613
ChemSpider	4447658
UNII	KC6BL281EN
ChEMBL	ChEMBL600325
CompTox Dashboard (EPA)	DTXSID5023532
ECHA InfoCard	100.006.702
Chemical and physical data
Formula	C₃₀H₄₂O₈
Molar mass	530.658 g·mol
3D model (JSmol)	Interactive image
SMILES O=C1OC=C(2CC3(2(CC43CCC5=C(CC54C)O6O(C)((6O)O)O)C)O)C=C1
InChI InChI=1S/C30H42O8/c1-16-24(32)25(33)26(34)27(37-16)38-19-8-11-28(2)18(14-19)5-6-22-21(28)9-12-29(3)20(10-13-30(22,29)35)17-4-7-23(31)36-15-17/h4,7,14-16,19-22,24-27,32-35H,5-6,8-13H2,1-3H3/t16-,19-,20+,21-,22+,24-,25+,26+,27-,28-,29+,30-/m0/s1 Key:MYEJFUXQJGHEQK-ALRJYLEOSA-N
(what is this?) (verify)

Proscillaridin is a cardiac glycoside, a kind of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). It is of the bufanolide type and can be obtained from plants of the genus Scilla and in Drimia maritima (Scilla maritima).

The aglycone of proscillaridin is scillarenin.

References

Kedra M, Kedrowa S (May 1968). "". Polski Tygodnik Lekarski. 23 (19): 714–6. PMID 4876207.

Bufo	Arenobufagin Bufotalin Cinobufagin Marinobufagin
Scilla	Proscillaridin Scilliroside
Kalanchoe	Daigremontianin

Digitalis	Acetyldigitoxin Acetyldigoxin Digitoxin Digoxin Lanatoside C Deslanoside Metildigoxin Gitoformate
Strophanthus	Ouabain (g-Strophanthin) k-Strophanthin Cymarin
Thevetia	Peruvoside

This drug article relating to the cardiovascular system is a stub. You can help Misplaced Pages by expanding it.