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 PGE1 (alprostadil) - topPGE2 (dinoprostone) - bottom | |
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Prostaglandin E is a family of naturally occurring prostaglandins that are used as medications.
Types include:
- Prostaglandin E1 also known as alprostadil
- Prostaglandin E2 also known as dinoprostone
Both types are on the World Health Organization's List of Essential Medicines.
Prostaglandin E play an important role in thermoregulation of the human brain. Decreased formation of prostaglandin E through inhibition of cyclooxygenase is the basis for the antipyretic of nonsteroidal anti-inflammatory drugs (NSAIDs).
References
- World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
External links
- "Alprostadil". Drug Information Portal. U.S. National Library of Medicine.
- "Dinoprostone". Drug Information Portal. U.S. National Library of Medicine.
- Prostaglandins+E at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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