Pruna is a surname. Notable people with the surname include:
- Aldo Pruna Díaz (born 1983), Cuban canoeist
- Anna Pruna i Grivé [ca] (born 1968), Spanish sports executive and athlete
- Antoni Pruna López [arz; ca] (born 1958), Spanish basketball player
- Domènec Pruna i Ozerans [ca] (born 1907–1974), Spanish filmmaker
- Pere Pruna i Ocerans [sc; es; fr; gl] (1904–1977), Spanish painter
- Ricard Pruna i Grivé [ca; nl] (born 1964), Spanish physician and surgeon
See also
- Cristina Mădălina Prună [pl; ro] (born 1984), Romanian politician
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