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Pyrobac-1 RNA motif

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Conserved RNA structure
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Pyrobac-1 RNA
Consensus secondary structure of Pyrobac-1 RNAs
Identifiers
SymbolPyrobac-1
RfamRF01722
Other data
RNA typesRNA
Domain(s)Pyrobaculum
PDB structuresPDBe

The Pyrobac-1 RNA motif is a conserved RNA structure discovered by bioinformatics. RNAs conforming to this motif have been found only in Pyrobaculum, a genus of archaea. Instances of the motif are hypothesized to function as non-coding RNAs. The motif has been shown to be part of sRNA202 and sRNA203 canonical and noncanonical pseudouridine guide RNAs (H/ACA RNA) in Pyrobaculum.

References

  1. Weinberg Z, Wang JX, Bogue J, et al. (March 2010). "Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea and their metagenomes". Genome Biol. 11 (3): R31. doi:10.1186/gb-2010-11-3-r31. PMC 2864571. PMID 20230605.
  2. Bernick, David L.; Dennis, Patrick P.; Höchsmann, Matthias; Lowe, Todd M. (March 2012). "Discovery of Pyrobaculum small RNA families with atypical pseudouridine guide RNA features". RNA. 18 (3): 402–411. doi:10.1261/rna.031385.111. ISSN 1469-9001. PMC 3285929. PMID 22282340.

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