| S-methyl-5'-thioadenosine deaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.5.4.31 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
S-methyl-5'-thioadenosine deaminase (EC 3.5.4.31, MTA deaminase, 5-methylthioadenosine deaminase) is an enzyme with systematic name S-methyl-5'-thioadenosine amidohydrolase. This enzyme catalyses the following chemical reaction
- S-methyl-5'-thioadenosine + H2O 5'-S-methyl-5'-thioinosine + NH3
5'-S-methyl-5'-thioinosine + NH3The enzyme from Thermotoga maritima also functions as S-adenosylhomocysteine deaminase (EC 3.5.4.28).
References
- Hermann JC, Marti-Arbona R, Fedorov AA, Fedorov E, Almo SC, Shoichet BK, Raushel FM (August 2007). "Structure-based activity prediction for an enzyme of unknown function". Nature. 448 (7155): 775–9. doi:10.1038/nature05981. PMC 2254328. PMID 17603473.
External links
- S-methyl-5'-thioadenosine+deaminase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
| Hydrolases: carbon-nitrogen non-peptide (EC 3.5) | |
|---|---|
| 3.5.1: Linear amides / Amidohydrolases | |
| 3.5.2: Cyclic amides/ Amidohydrolases | |
| 3.5.3: Linear amidines/ Ureohydrolases | |
| 3.5.4: Cyclic amidines/ Aminohydrolases | |
| 3.5.5: Nitriles/ Aminohydrolases | |
| 3.5.99: Other | |
| Enzymes | |
|---|---|
| Activity | |
| Regulation | |
| Classification | |
| Kinetics | |
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