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Salicylanilide

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Salicylanilide
Names
Preferred IUPAC name 2-Hydroxy-N-phenylbenzamide
Other names 2-Hydroxybenzanilide
Identifiers
CAS Number
3D model (JSmol)
Beilstein Reference 1108135
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.001.571 Edit this at Wikidata
EC Number
  • 201-727-8
KEGG
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16)Key: WKEDVNSFRWHDNR-UHFFFAOYSA-N
  • InChI=1/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16)Key: WKEDVNSFRWHDNR-UHFFFAOYAI
SMILES
  • C1=CC=C(C=C1)NC(=O)C2=CC=CC=C2O
Properties
Chemical formula C13H11NO2
Molar mass 213.236 g·mol
Appearance White to off-white crystalline solid
Melting point 136 to 138 °C (277 to 280 °F; 409 to 411 K)
Hazards
GHS labelling:
Pictograms GHS07: Exclamation markGHS09: Environmental hazard
Signal word Warning
Hazard statements H315, H319, H335, H400
Precautionary statements P261, P264, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P391, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒N verify (what is  ?) Infobox references
Chemical compound

Salicylanilide is a chemical compound which is the amide of salicylic acid and aniline. It is classified as both a salicylamide and an anilide.

Derivatives of salicylanilide have a variety of pharmacological uses. Chlorinated derivatives including niclosamide, oxyclozanide, and rafoxanide are used as anthelmintics, especially as flukicides. Brominated derivatives including dibromsalan, metabromsalan, and tribromsalan are used as topical antibacterials and antifungals.


References

  1. Salicylanilide at chemicalland21.com
  2. "Salicylanilide". pubchem.ncbi.nlm.nih.gov. Retrieved 13 December 2021.
  3. Salicylanilides at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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