Saprykin (Russian: Сапры́кин) is a Russian masculine surname, its feminine counterpart is Saprykina. It may refer to
- Aleksandr Saprykin (1946–2021), Soviet volleyball player
- Haroldas Saprykinas (born 1995), Lithuanian basketball player
- Igor Saprykin (born 1992), Russian ice hockey goaltender
- Oksana Saprykina (born 1979), Ukrainian road cyclist
- Oleg Saprykin (born 1981), Russian ice hockey player
- Yevgeni Saprykin (born 1970), Soviet and Russian footballer
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