Shathru (lit. 'enemy') may refer to:
- Shathru (1985 film), an Indian Malayalam-language film
- Shathru (2013 film), an Indian Kannada-language film
- Sathru (2019 film), an Indian Tamil-language action thriller film
See also
- Shatruvu (disambiguation)
- Shatru (disambiguation)
- Shotru, a 2011 Indian Bengali-language film
- Sathru (2019 film), an Indian Tamil-language film
- Sathrusamhaaram, a 1978 Indian Malayalam-language film
- Shatrughna, the brother of Rama in the ancient Indian epic Ramayana
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